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628-89-7 - 2-(2-Chloroethoxy)ethanol, 99% - Diethylene glycol monochlorohydrin - 2-(2-Hydroxyethoxy)ethyl chloride - A13074 - Alfa Aesar

A13074 2-(2-Chloroethoxy)ethanol, 99%

CAS Number
628-89-7
Synonyms
Diethylene glycol monochlorohydrin
2-(2-Hydroxyethoxy)ethyl chloride

Size Price ($) Quantity Availability
50g 33.27
250g 109.80
1000g 385.20
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2-(2-Chloroethoxy)ethanol, 99%

MDL
MFCD00002870
EINECS
211-059-9

Chemical Properties

Formula
C4H9ClO2
Formula Weight
124.57
Boiling Point
185°
Flash Point
90°(194°F)
Density
1.180
Refractive Index
1.4535
Solubility
Miscible with water.

Applications

2-(2-Chloroethoxy)ethanol is employed in the preparation of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine and 2-(2-azidoethoxy)ethanol.

Notes

Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong bases.

Literature References

Kotb, E. R.; Abbas, H. A. S.; Flefel, E. M.; Sayed, H. H.; Abdelwahed, N. A. M. Month 2015 Utility of Hantzsch Ester in Synthesis of Some 3,5-Bis-dihydropyridine Derivatives and Studying Their Biological Evaluation. J. Heterocycl. Chem. 2015, 52 (5), 1531-1539.

Yang, Y.; Fu, H.; Cui, M.; Peng, C.; Liang, Z.; Dai, J.; Zhang, Z.; Lin, C.; Liu, B. Preliminary evaluation of fluoro-pegylated benzyloxybenzenes for quantification of beta-amyloid plaques by positron emission tomography. Eur. J. Med. Chem. 2015, 104, 86-96.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335-H227

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Combustible liquid.

Precautionary Statements: P210-P261-P280-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
506015
Harmonized Tariff Code
2909.49
TSCA
Yes
RTECS
KK1350000

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