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1-Acetylferrocene was originally used in military or space field as an additive in rocket propellant, to promote the burning rate. Its ferrocenyl derivative has wide applications to biological and medical fields such as ferrocene-modified beta-lactam because of its physiological activity of anti-malarial, anti-tumor, bactericidal, anti-inflammatory, treatment of anemia, inhibition of enzymatic activity and so on by virtue of its unique structure and diverse properties.
R.V.Singh; S.C.Joshi; Anita Gajraj; Pooja Nagpal. Studies of biologically potent organotin(IV) and organosilicon(IV) complexes of a sulfur donor ligand derived from 1-acetylferrocene. Applied Organometallic Chemistry. 2002, 16, (12),713-720
A procedure for the conversion of methyl ketones to terminal acetylenes is exemplified by reaction with POCl3 - DMF to give (2-formyl-1-chlorovinyl)ferrocene which, by elimination with NaOH, affords ethynylferrocene: J. Organomet. Chem., 6, 173 (1966); Org. Synth. Coll., 9, 411 (1998).
Hazard Statements: H300-H310
Fatal if swallowed. Fatal in contact with skin.
Precautionary Statements: P262-P280h-P301+P310a-P321-P405-P501a
Do not get in eyes, on skin, or on clothing. Wear protective gloves/clothing. IF SWALLOWED: Immediately call a POISON CENTER/doctor Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.