Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A13135 Maleimide, 98+%

CAS Number
541-59-3
Synonyms
2,5-Dioxo-3-pyrroline
1H-Pyrrole-2,5-dione

Stock No. Size Price ($) Quantity Availability
A13135-06 5g 46.70
A13135-14 25g 183.00
A13135-18 50g 326.00
A13135-30 250g 1431.00
Add to Cart Bulk/Specialty Print Quote View Item

Maleimide, 98+%

MDL
MFCD00005494
EINECS
208-787-4

Chemical Properties

Formula
C4H3NO2
Formula Weight
97.07
Melting point
90-94°
Boiling Point
97-103/5mm
Density
1.249
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

Reacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry.

Notes

Store in a cool place. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.

Literature References

Stereoselective Diels-Alder reaction with an exocyclic diene has been used in the synthesis of a cyclohexannulated [5.3.1]propellane as a precursor of an ABC ring analogue of paclitaxel (Taxol): J. Chem. Soc., Chem. Commun., 1395 (1995).

Haralampiev, I.; Mertens, M.; Schwarzer, R.; Herrmann, A.; Volkmer, R.; Wessig, P.; Müller, P. Recruitment of SH-Containing Peptides to Lipid and Biological Membranes through the Use of a Palmitic Acid Functionalized with a Maleimide Group. Angew. Chem. Int. Ed. 2015, 54 (1), 323-326.

Kanyong, P.; Sun, G.; Rösicke, F.; Syritski, V.; Panne, U.; Hinrichs, K.; Rappich, J. Maleimide functionalized silicon surfaces for biosensing investigated by in-situ IRSE and EQCM. Electrochem. Commun. 2015, 51, 103-107.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H312-H314-H317-H332-H335

Toxic if swallowed. Harmful in contact with skin. Causes severe skin burns and eye damage. May cause an allergic skin reaction. Harmful if inhaled. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P270-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
106910
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2925.19
TSCA
Yes
RTECS
ON4800000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware