Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

82911-69-1 - N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98% - 9-Fluorenylmethyl N-succinimidyl carbonate - Fmoc-ONSu - A13143 - Alfa Aesar

A13143 N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%

CAS Number
82911-69-1
Synonyms
9-Fluorenylmethyl N-succinimidyl carbonate
Fmoc-ONSu

Size Price ($) Quantity Availability
1g 23.59
5g 61.49
25g 249.26
Add to Cart Add to Quote Request View Item

N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%

MDL
MFCD00010733
EINECS
433-520-5

Chemical Properties

Formula
C19H15NO5
Formula Weight
337.34
Melting point
150-153°
Sensitivity
Moisture Sensitive
Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide.

Applications

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides.

Notes

Store in a cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids.

Literature References

Reagent for the preparation of Fmoc derivatives of amino acids, avoiding problems arising from mixed anhydride formation; preferred especially for the protection of hydroxy amino acids: Can. J. Chem., 60, 976 (1982); Biopolymers, 22, 2157 (1983); Synthesis, 671 (1978). For peptide reagents, see Appendix 6.

Bartolami, E.; Gilles, A.; Dumy, P.; Ulrich, S. Synthesis of alpha-PNA containing a functionalized triazine as nucleobase analogue. Tetrahedron Lett. 2015, 56 (18), 2319-2323.

Wang, N.; Seko, A.; Takeda, Y.; Ito, Y. Preparation of asparagine-linked monoglucosylated high-mannose-type oligosaccharide from egg yolk. Carbohydr. Res. 2015, 411, 37-41.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317-H411-H401

Harmful if swallowed. May cause an allergic skin reaction. Toxic to aquatic life with long lasting effects. Toxic to aquatic life.

Precautionary Statements: P261-P273-P280-P264-P270-P301+P312-P363-P321-P333+P313-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3569540
Hazard Class
9
Packing Group
III
Harmonized Tariff Code
2925.19
TSCA
No

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware