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A13205 endo-N-Hydroxy-5-norbornene-2,3-dicarboximide, 97%

CAS Number
21715-90-2
Synonyms
HONB
endo-N-Hydroxybicyclo[2.2.1]hept-5-ene-2,3-dicarboximide

Stock No. Size Price ($) Quantity Availability
A13205-09 10g 29.10
A13205-18 50g 115.00
A13205-30 250g 443.00
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endo-N-Hydroxy-5-norbornene-2,3-dicarboximide, 97%

MDL
MFCD00065691
EINECS
244-538-6

Chemical Properties

Formula
C9H9NO3
Formula Weight
179.18
Melting point
166-170°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in ethanol

Applications

It decreases racemization in peptide synthesis and inhibits formation of N-acylureas.

Notes

Store at room temperature. Incompatible with oxidizing agents.

Literature References

H. Michael Petrassi.; K. Barry Sharpless.; Jeffery W. Kelly. The Copper-Mediated Cross-Coupling of Phenylboronic Acids and N-Hydroxyphthalimide at Room Temperature:? Synthesis of Aryloxyamines. Org. Lett. 2001, 3 (1),139-142 .

Haoxi Ben.; Arthur J. Ragauskas. Pyrolysis of Kraft Lignin with Additives.Energy Fuels. 2011, 24 (10), 4662-4668 .

Reportedly superior to N-Hydroxysuccinimide, A10312 as a racemization suppressant in peptide synthesis: Chem. Pharm. Bull., 22, 1857 (1974); 26, 585 (1978). See Appendix 6.

Reagent for preparation of O-alkylhydroxylamines by O-alkylation and cleavage with hydrazine: Bull. Soc. Chim. Fr., 833 (1976). Compare N-Hydroxyphthalimide, A13862.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
13540
Harmonized Tariff Code
2925.19
TSCA
Yes

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