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64-86-8 - Colchicine, 95% (dry wt.) - A13240 - Alfa Aesar

A13240 Colchicine, 95% (dry wt.)

CAS Number
64-86-8
Synonyms

Size Price ($) Quantity Availability
1g 79.02
5g 264.22
25g 1018.80
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Colchicine, 95% (dry wt.)

MDL
MFCD00078484
EINECS
200-598-5

Chemical Properties

Formula
C22H25NO6
Formula Weight
399.44
Melting point
ca 150° dec.
Sensitivity
Light Sensitive
Solubility
Soluble in water and alcohol. Sparingly soluble in ether.

Applications

Colchicine is used as an anti-inflammatory agent for long-term treatment of behçet's disease. It is used for constipation-predominant irritable bowel syndrome in women, and for treatment of severe or persistent aphthous stomatitis (canker sores).

Notes

Incompatible with strong oxidizing agents and mineral acids.

Literature References

Hwang, D.; Wang, J.; Li, W.; Miller, D. D. Structural Optimization of Indole Derivatives Acting at Colchicine Binding Site as Potential Anticancer Agents. ACS Med. Chem. Lett. 2015, 6 (9), 993-997.

Kuroiwa, K.; Ishii, H.; Matsuno, K.; Asai, A.; Suzuki, Y. Synthesis and Structure-Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents. ACS Med. Chem. Lett. 2015, 6 (3), 287-291.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H340

Fatal if swallowed. May cause genetic defects.

Precautionary Statements: P201-P281-P264-P270-P301+P310-P308+P313-P321-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF exposed or concerned: Get medical advice/attention. Specific treatment (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2471
Beilstein
2228813
Hazard Class
6.1
Packing Group
I
Harmonized Tariff Code
2939.99
TSCA
Yes
RTECS
GH0700000

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