I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Methanesulfonic anhydride is used to prepare methylsulfonyl esters called as mesylates. It finds application in the reaction of aromatic alkylation. It reacts with dimethylsulfoxide to get sulfoxonium complex, which is a useful oxidizing agent.
More powerful sulfonylating reagent than the sulfonyl chloride, also avoiding possible displacement of sulfonate by halide. With a catalytic amount of the acid effects mesylation of deactivated aromatics such as 1,3-dichlorobenzene: Chem. Lett., 395 (1988); mesyl chloride is ineffective.
Primary and secondary alcohols may be oxidized to carbonyl compounds by sulfonic anhydrides in DMSO: J. Org. Chem., 39, 1977 (1974). For related methods, see Dimethyl sulfoxide, A13280.
Liu, W., Tilley, T. D. Sterically Controlled Functionalization of Carbon Surfaces with- C6H4CH2X (X= OSO2Me or N3) Groups for Surface Attachment of Redox-Active Molecules. Langmuir 2015, 31 (3), 1189-1195.
Hu, Y.; Zhang, F.; Zhang, C.; Zhang, M. Anti-inflammatory Properties of an Active Sesquiterpene Lactone and its Structure-Activity Rela-tionship. Med chem 2015, 5, 354-360.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.