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4-Methylbenzeneboronic acid, is a commonly used chemical in Suzuki coupling reactions. It is also used as an intermediate in pharmaceutical industry
Z Jia.; JW Quail.; VK Arora.; JR Dimmock. Structure of 3, 5-bis (benzylidene)-1-methyl-4-piperidone methobromide hemiethanol solvate. Tetrahedron Letters. 2001, 42,(29) 4751-4754.
SD Taylor.;CC Kotoris.; AN Dinaut.; Q Wang. Potent non-peptidyl inhibitors of protein tyrosine phosphatase 1B. Bioorganic & Medicinal Chemistry. 1998, 6,(9), 1457-1468.
GC reagent for diols: J. Chromat., 158, 33 (1978); 186, 307 (1979).
For general chemistry of boronic acids, see Appendix 5.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant