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It is is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. They are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization.
AB Smith.; S Sasho.; BA Barwis.; P Sprengeler. Design and synthesis of a tetrahydropyran-based inhibitor of mammalian ribonucleotide reductase. Bioorganic & Medicinal Chemistry Letters. 1998, 8,(22), 3133-3136.
HK Hsieh.; TH Lee.; JP Wang.; JJ Wang.; CN Lin. Synthesis and anti-inflammatory effect of chalcones and related compounds. Pharmaceutical research. 1998, 15,(1), 39-46.
Alcohols have been protected as their tetrahydropyranyl ethers under non-acidic, free radical conditions: Synlett, 207 (1995); cf 3,4-Dihydro-2H-pyran, L02731.
Hazard Statements: H225
Highly flammable liquid and vapour.
Precautionary Statements: P210-P280a-P240-P241-P303+P361+P353-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Dispose of contents/container in accordance with local/regional/national/international regulations.