I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Cyclization in the presence of dichlorodimethylsilane and triflic acid leads to 2,5-dimethyl-1,3,4-oxadiazole. The active species, formed in situ, is dimethylsilyl ditriflate: Synth. Commun., 18, 1247 (1988). The same cyclization can be effected by HMDS in combination with F-: Synth. Commun., 19, 2321 (1989)./n
Hazard Statements: H302-H312-H332-H315-H319-H335
Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.