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Cycloheptanone is used as a precursor for the synthesis of pharmaceuticals. A spasmolytic agent and vasodilator is produced from this chemical. They are also used in certain stereospecific enzymatic reactions.
MS Mubarak.; TB Jennermann. Catalytic Reduction of Phenyl-Conjugated Acetylenic Halides by Nickel (I) Salen: Cyclization versus Coupling. European Journal of Organic Chemistry. 2007, 20047,(32), 5346-5352.
KJ Shea.; DY Sasaki. On the control of microenvironment shape of functionalized network polymers prepared by template polymerization. Journal of the American Chemical Society. 1989, 111,(9), 3442-3444.
Reaction with tributyl[(methoxymethoxy)methyl]stannane (see Tri-n-butyltin hydride, A13298) is the equivalent of attack by hydroxymethyl anion: Org. Synth. Coll., 9, 493 (1998):
Hazard Statements: H226-H302-H318
Flammable liquid and vapour. Harmful if swallowed. Causes serious eye damage.
Precautionary Statements: P210-P280a-P303+P361+P353-P305+P351+P338-P310a-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor Dispose of contents/container in accordance with local/regional/national/international regulations.