Tetramethyl methylenediphosphonate is used in the preparation of phosphonate analogue of ribose-1-phosphate.
Marquick, A. L.; Montero, J. L.; Lebrun, A.; Barragan-Montero, V. Straightforward synthesis towards mono and bis-phosphonic acid functionalised beta-cyclodextrins. Tetrahedron 2015, 71 (10), 1616-1621.
A Bisceglia, J.; R Orelli, L. Recent Progress in the Horner-Wadsworth-Emmons Reaction. Curr. Org. Chem. 2015, 19 (9), 744-775.
Hazard Statements: H302-H315-H319
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: P280h-P305+P351+P338
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.