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A13461 5-Sulfosalicylic acid dihydrate, 98%

CAS Number
5965-83-3
Synonyms
2-Hydroxy-5-sulfobenzoic acid dihydrate

Stock No. Size Price ($) Quantity Availability
A13461-30 250g 37.30
A13461-0B 1000g 112.00
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5-Sulfosalicylic acid dihydrate, 98%

MDL
MFCD00007508
EINECS
202-555-6

Chemical Properties

Formula
C7H6O6SH•2H2O
Formula Weight
254.22 (218.19anhy)
Melting point
103-112°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in water

Applications

5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([?]-5-sulfonatosalicylato)tricopper(II)] trihydrate]. Also used as an intermediate synthesis of bulk drugs, surfactant and additive for lubricating grease.

Notes

Light Sensitive, store in dark. Store in cool, dry place in tightly closed container. Store away from strong bases and oxidizing agent.

Literature References

David L Chin et. al. Rapid determination of PEGylated liposomal doxorubicin and its major metabolite in human plasma by ultraviolet-visible high-performance liquid chromatography. Journal of Chromatography B. 2002, 779(2), 259-269.

Fan S-R; and Zhu L-G. Poly [[tris (di-2-pyridylamine) tris (-5-sulfonatosalicylato) tricopper (II)] trihydrate]. Acta Crystallogr. Sect. E Struct. Rep. Online, 2004, 61 (1), m174-m176.

Deproteinization reagent: J. Chromat., 74, 255 (1973); 570, 285 (1991). Spray reagent for detection of sugars on TLC: J. Chromat., 315, 401 (1985).

Acid catalyst, alternative to tosic acid in certain esterification and acetalization reactions: Org. Synth. Coll., 1, 246 (1941); J. Am. Chem. Soc., 76, 743 (1954); 80, 6613 (1958); J. Org. Chem., 28, 2425 (1963).

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H314

Harmful if swallowed. Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,8964
Beilstein
650741
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2918.29
TSCA
Yes
RTECS
VO6500000

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