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5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts. 5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent
M. Scendo, D. Poddebniak.; J. Malyszko. Bennett. Indole and 5-chloroindole as inhibitors of anodic dissolution and cathodic deposition of copper in acidic chloride solutions. Journal of Applied Electrochemistry. 2003, 33, (3-4), 287-293.
Robert M. Moriarty.; Yi Yin. Ku.; U. S. Gill. Synthesis and characterization of new (.eta.6-substituted indole)(.eta.5-cyclopentadienyl)ruthenium complexes. Nucleophilic displacement upon (.eta.6-4- or .eta.6-5-chloroindole)(.eta.5-cyclopentadienyl)ruthenium(II) hexafluorophosphates. Organometallics. 1988, 7, (3), 660-665.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.