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Chlorotriphenylsilane is used as a silylating agent. It is also used as a pharmaceutical intermediate.
Raymond C. Petersen.; Sidney D. Ross. Displacement Reactions on Silicon. The Reaction of 2-Propanol with Chlorotriphenylsilane in Carbon Tetrachloride. J. Am. Chem. Soc. 1963, 85 (20), 3164-3167.
Henry Gilman.; Glen D. Lichtenwalter. Cleavage of Symmetrically Substituted Disilanes by Lithium in Tetrahydrofuran. J. Am. Chem. Soc. 1958, 80 (3), 608-611.
Silylating agent: J. Chem. Soc., 3403 (1963); see Appendix 4. The stability of the bulky triphenylsilyl (TPS) ethers to basic hydrolysis is similar to TMS, but they are about 400x more stable to acid hydrolysis. Suitable conditions for their cleavage include: ethanolic NaOH; AcOH - water - THF at 70o: Chem. Lett., 1499 (1979); and TBAF: J. Am .Chem. Soc., 108, 3827 (1986).
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.