Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

769-42-6 - 1,3-Dimethylbarbituric acid, 99% (dry wt.), water <6% - 1,3-Dimethyl-2,4,6-pyrimidinetrione - A13692 - Alfa Aesar

A13692 1,3-Dimethylbarbituric acid, 99% (dry wt.), water <6%

CAS Number
769-42-6
Synonyms
1,3-Dimethyl-2,4,6-pyrimidinetrione

1,3-Dimethylbarbituric acid, 99% (dry wt.), water <6%

MDL
MFCD00006675
EINECS
212-211-7

Chemical Properties

Formula
C6H8N2O3
Formula Weight
156.14
Melting point
121-123°
Solubility
Soluble in water.

Applications

1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione derivatives.

Notes

Incompatible with strong oxidizing agents.

Literature References

Shih, Y. C.; Tsai, P. H.; Hsu, C. C.; Chang, C. W.; Jhong, Y.; Chen, Y. C.; Chien, T. C. Biomimetic Approach toward the Total Synthesis of rac-2-(Acylmethylene)pyrrolidine Alkaloids. J. Org. Chem. 2015, 80 (13), 6669-6678.

Myochin, T.; Hanaoka, K.; Iwaki, S.; Ueno, T.; Komatsu, T.; Terai, T.; Nagano, T.; Yasuteru Urano,Y. Development of a Series of Near-Infrared Dark Quenchers Based on Si-rhodamines and Their Application to Fluorescent Probes. J. Am. Chem. Soc. 2015, 137 (14), 4759-4765.

GHS Hazard and Precautionary Statements

Hazard Statements: H318-H302

Causes serious eye damage. Harmful if swallowed.

Precautionary Statements: P280-P264-P270-P305+P351+P338-P310-P301+P312-P330-P501a

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
139810
Harmonized Tariff Code
2933.54
TSCA
Yes

Recommended

  • A10934

    Barbituric acid, 99%
  • A11766

    Allyl bromide, 99%, stab. with 300-1000ppm Propylene oxide
  • A12206

    1,3-Indanedione, 97%
  • A12799

    2,6-Dimethyl-4-pyrone, 99%
  • B25395

    Methyl 4-iodo-3-methylbenzoate, 98%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware