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L-(-)-Malic acid is used as Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece. It also acts as active ingredient in many sour or tart foods. It is used as synthesizing disincrustant and fluorescent whitening agent. It aids in the production of polyester and alcohol acid resins.
Isao Takata; Kozo Yamamoto; Tetsuya Tosa; Ichiro Chibata. Immobilization of Brevibacterium flavum with carrageenan and its application for continuous production of l-malic acid.Enzyme and Microbial Technology.1980, 2 30-36.
F. A. T. Anet. The Configuration of Deuterio-l-malic acid Produced Enzymatically. Synthesis of Threo-3-deuterio-dl-malic acid. J. Am. Chem. Soc.1960, 82 (4), 994-995.
Resolving agent for chiral amines; see, for example: Org. Synth. Coll., 2, 506 (1943).
Hazard Statements: H315-H318-H335
Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant