Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A13725 1-Butylboronic acid, 98%

CAS Number
4426-47-5
Synonyms
n-Butaneboronic acid

Stock No. Size Price ($) Quantity Availability
A13725-03 1g 26.20
A13725-06 5g 80.10
A13725-14 25g 305.00
Add to Cart Bulk/Specialty Print Quote View Item

1-Butylboronic acid, 98%

MDL
MFCD00002106
EINECS
224-607-7

Chemical Properties

Formula
CH3CH2CH2CH2B(OH)2
Formula Weight
101.94
Melting point
92-96°
Storage & Sensitivity
Keep Cold. Hygroscopic. Air Sensitive.
Solubility
Soluble in water.

Applications

1-Butylboronic acid is used as a reagent for preparation of volatile derivatives of diols, e.g. carbohydrates, for GC and mass spectrometry and to prepare chiral oxazaborolidines. It is a precursor to unsymmetric borinic acids, which are inhibitors of serine proteases. Can be used as a transport carrier in membrane-based sugar separations and as an analytical reagent in the determination of serum glucose.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. It is hygroscopic in nature. Incompatible with oxidizing agents. Store under dry inert gas.

Literature References

Franck Picard.; Tobias Schulz.; Rolf W. Hartmann. 5-Phenyl substituted 1-methyl-2-pyridones and 4?-substituted biphenyl-4-carboxylic acids. synthesis and evaluation as inhibitors of steroid-5α-reductase type 1 and 2. Bioorganic & Medicinal Chemistry. 2002, 10 (2), 437-448.

Zhao Yongliang.; Zhao Fengying.; Li Qiang.; Gao Deqing. Synthesis, Characterization and Fluorescence Properties of Europium, Terbium Complexes with Biphenyl-4-Carboxylic Acid and o-Phenanthroline. Journal of Rare Earths. 2006, 24 (1), 18-22.

Reagent for preparation of volatile derivatives of diols, e.g. carbohydrates, for GC and mass spectrometry: J. Chromat., 54, 193 (1971); J. Chromat. Sci., 9, 18 (1971); Gas Chromat., 129 (1968).

In combination with (S)-(-)-ɑ,ɑ-Diphenyl­prolinol, L09217, or its enantiomer (9218), oxazaborolidine catalysts are generated in situ, for use in highly enantioselective reductions: Tetrahedron Lett., 33, 4141 (1992). The same system has been employed in the synthesis of chiral monosubstituted oxiranes: Tetrahedron Lett., 34, 5227 (1993). See also (S)-2-Methyl-CBS-oxazaborolidine monohydrate, L09219, and Appendix 5.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1733489
Harmonized Tariff Code
2931.90
TSCA
No

Recommended

  • A18304

    2-Methyl-2-butanol, 98%
  • A18481

    Styrene, 99%, stab. with 10-15ppm 4-tert-butylcatechol
  • B22446

    1-Hexylboronic acid, 97%
  • B23842

    Furan-2-boronic acid, 97%
  • H26893

    3,5-Dimethylisoxazole-4-boronic acid, 97%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware