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15761-39-4 - N-Boc-L-proline, 99% - Boc-Pro-OH - N-(tert-Butoxycarbonyl)-L-proline - A13744 - Alfa Aesar

A13744 N-Boc-L-proline, 99%

CAS Number
15761-39-4
Synonyms
Boc-Pro-OH
N-(tert-Butoxycarbonyl)-L-proline

Size Price ($) Quantity Availability
5g 22.32
25g 72.10
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N-Boc-L-proline, 99%

MDL
MFCD00037324
EINECS
239-848-3

Chemical Properties

Formula
C10H17NO4
Formula Weight
215.25
Melting point
132-136°
Solubility
Soluble in acetic acid.

Applications

N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV).

Notes

Moisture and light sensitive. Incompatible with strong oxidizing agents.

Literature References

Sultane, P. R.; Mete, T. B.; Bhat, R. G. A convenient protocol for the deprotection of N-benzyloxycarbonyl (Cbz) and benzyl ester groups. Tetrahedron Lett. 2015, 56 (16), 2067-2070.

Wang, H.; Li, N.; Yan, Z.; Zhang, J.; Wan, X. Synthesis and properties of novel helical 3-vinylpyridine polymers containing proline moieties for asymmetric aldol reaction. RSC Adv. 2015, 5 (65), 52410-52419.

Other References

Beilstein
15828
Harmonized Tariff Code
2933.99
TSCA
Yes

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