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4-Aminobenzonitrile is used as an amino substituted benzonitrile with hypotensive activity and as a radioprotective agent. It is also used as a derivatization reagent in the capillary zone electrophoretic analysis of aldoses, ketoses and uronic acid. Further, it is used in the preparation of methacrylic monomers containing pendant azobenzene structures and polythiophenes containing an azobenzene moiety in the side-chain.
Betz, T.; Zinn, S.; Graneek, J. B.; Schnell, M. Nuclear Quadrupole Coupling Constants of Two Chemically Distinct Nitrogen Atoms in 4-Aminobenzonitrile. J. Phys. Chem. A 2014, 118 (28), 5164-5169.
Perveaux, A.; Castro, P. J.; Lauvergnat, D.; Reguero, M.; Lasorne, B. Intramolecular Charge Transfer in 4-Aminobenzonitrile Does Not Need the Twist and May Not Need the Bend. J. Phys. Chem. Lett. 2015, 6 (8), 1316-1320.
Hazard Statements: H301-H312-H319
Toxic if swallowed. Harmful in contact with skin. Causes serious eye irritation.
Precautionary Statements: P280h-P305+P351+P338-P309-P310a
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: