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2777-65-3 - 10-Undecynoic acid, 96% - A13815 - Alfa Aesar

A13815 10-Undecynoic acid, 96%

CAS Number
2777-65-3
Synonyms

Size Price ($) Quantity Availability
5g 87.55
25g 312.30
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10-Undecynoic acid, 96%

MDL
MFCD00014389
EINECS
220-471-8

Chemical Properties

Formula
HC≡C(CH2)8CO2H
Formula Weight
182.26
Melting point
40-43°
Boiling Point
174-176°/4mm
Flash Point
161°(321°F)
Solubility
Sparingly Soluble in water.

Applications

10-Undecynoic acid may be employed as a biochemical probe in an assay for the microsomal hydroxylation of lauric acid (LA), based on HPLC with flow-through radiochemical detection. It was employed as model compound to investigate the microwave assisted surface click reactions catalyzed with Cu(II)/sodium L-ascorbate. It is reported as highly selective irreversible inhibitor of hepatic ω- and ω-1-lauric acid hydroxylases.

Notes

Store at 4°C. Store away from incompatible materials such as oxidizing agents

Literature References

P R Ortiz de Montellano; N O Reich. Specific inactivation of hepatic fatty acid hydroxylases by acetylenic fatty acids.Journal of Biological Chemistry.1984, 259 (7), 4136-4141.

Lenart J; Pikuła S 10-Undecynoic acid, an inhibitor of cytochrome P450 4A1, inhibits ethanolamine-specific phospholipid base exchange reaction in rat liver microsomes.Acta Biochimica Polonica.1999, 46 (1), 203-210.

For use in the synthesis of long-chain ω-hydroxy acids, by acetylenic coupling with bromoacetylenic alcohols (from hypobromite bromination of alkynols), see: Synthesis, 230 (1984).

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Beilstein
1704918
Harmonized Tariff Code
2916.19
TSCA
No
RTECS
YQ3683000

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