Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

605-65-2 - Dansyl chloride, 97+% - 5-Dimethylaminonaphthalene-1-sulfonyl chloride - DNSCl - A13828 - Alfa Aesar

A13828 Dansyl chloride, 97+%

CAS Number
605-65-2
Synonyms
5-Dimethylaminonaphthalene-1-sulfonyl chloride
DNSCl

Size Price ($) Quantity Availability
1g 30.69
5g 94.55
25g 379.04
Add to Cart Add to Quote Request View Item

Dansyl chloride, 97+%

MDL
MFCD00003985
EINECS
210-092-6

Chemical Properties

Formula
C12H12ClNO2S
Formula Weight
269.75
Melting point
69-75°
Sensitivity
Moisture Sensitive
Solubility
Soluble in dimethyl fluoride, acetone, chloroform, pyridine, benzene and dioxane. Insoluble in water.

Applications

Dansyl chloride is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.

Notes

Store in cool place. Moisture sensitive. Incompatible with strong bases.

Literature References

Reagent for the preparation of fluorescent derivatives of amino acids and proteins: Biochemistry, 9, 3878 (1970); Anal. Biochem., 53, 132 (1973); 66, 104 (1975).

Lachapelle, A. R.; Solliec, M.; Sauve, S. Determination of BMAA and three alkaloid cyanotoxins in lake water using dansyl chloride derivatization and high-resolution mass spectrometry. Anal. Bioanal. Chem. 2015, 407 (18), 5487-5501.

Karabacak, M.; Cinar, M.; Kurt, M.; Poiyamozhi, A.; Sundaraganesan, N. The spectroscopic (FT-IR, FT-Raman, UV and NMR) first order hyperpolarizability and HOMO-LUMO analysis of dansyl chloride. Spectrochim. Acta, Part A 2014, 117, 234-244.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P280-P303+P361+P353-P305+P351+P338-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.

Other References

Merck
14,2814
Beilstein
2217205
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2921.49
TSCA
Yes
RTECS
QK3688000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware