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1-Fluoro-2-nitrobenzene is an intermediate in the synthetic preparations of various pharmaceutical goods.
Elaine K. Fukuda; Robert T. McIverJr. Relative electron affinities of substituted benzophenones, nitrobenzenes, and quinones.J. Am. Chem. Soc.1985, 107 (8), 2291-2296.
The activating effect of aryl halides by o- or p-nitro groups is most pronounced for aryl fluorides, e.g. reacts readily with arylamines in a convenient synthesis of 2-nitrodiarylamines: Synthesis, 215 (1980).
Hazard Statements: H301-H311-H331-H315-H319-H373
Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P280-P301+P310a-P305+P351+P338-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.