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Triphenylmethylamine was used to prepare diamondoid porous organic salt.1 It was also used in preparation of N-tritylated β-amino alcohols, useful building blocks in organic synthesis. It is used in the preparation of trityl- cysteine analogs as inhibitors of human mitotic kinesin.
Atsushi Yamamoto; Tetsuya Hasegawa; Tomoya Hamada; Tomofumi Hirukawa; Ichiro Hisaki; Mikiji Miyata; Norimitsu Tohnai. Role-allocated combination of two types of hydrogen bonds towards constructing a breathing diamondoid porous organic salt. Chemistry: A European Journal. 2013, 19 (9), 3006-3016.
Sushil K. Sharma; Michael F. Songster; Tracey L. Colpitts; Peter Hegyes; George Barany; Francis J. Castellino. Reductive amination with tritylamine as an ammonia equivalent: efficient preparation of the 5-(4-(9-fluorenylmethyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)valeric acid (PAL) handle for peptide synthesis. J. Org. Chem., 1993, 58 (18), 4993-4996.
Protected form of ammonia: the trityl group is removable by strong acid. For use in the synthesis of 1-aminoalkanephosphonic esters or acids, see: Synthesis, 370 (1988):
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.