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600-22-6 - Methyl pyruvate, 98% - Pyruvic acid methyl ester - Methyl 2-oxopropionate - A13966 - Alfa Aesar

A13966 Methyl pyruvate, 98%

CAS Number
600-22-6
Synonyms
Pyruvic acid methyl ester
Methyl 2-oxopropionate

Size Price ($) Quantity Availability
25g 29.91
100g 81.58
500g 300.93
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Methyl pyruvate, 98%

MDL
MFCD00008754
EINECS
209-987-4

Chemical Properties

Formula
C4H6O3
Formula Weight
102.09
Boiling Point
135-137°
Flash Point
39°(102°F)
Density
1.123
Refractive Index
1.4040
Solubility
Soluble in chloroform, methanol, ether, alcohol. Slightly soluble in water.

Applications

Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors. It increases free calcium ion concentration in the cytosol of pancreatic cells. It is used in the preparation of dimethyl 2,3-dimethylenebutanedioate.

Notes

Store away from oxidizing agent, heat.

Literature References

G. Bond, P.A. Meheux; A. Ibbotson; P.B. Wells. Origin of enhanced rate in the platinum-catalysed enantioselective hydrogenation of methyl pyruvate. Catalysis Today. 1991, 10 (3), 371-378.

I.M. Sutherland; A. Ibbotson; R.B. Moyes; P.B. Wells. Enantioselective hydrogenation I. Surface conditions during methyl pyruvate hydrogenation catalyzed by cinchonidine-modified platinum/silica (EUROPT-1). Journal of Catalysis. 1990, 125 (1), 77-88.

GHS Hazard and Precautionary Statements

Hazard Statements: H226

Flammable liquid and vapour.

Precautionary Statements: P261

Avoid breathing dust/fume/gas/mist/vapours/spray.

Other References

Merck
14,8021
Beilstein
1361953
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2918.30
TSCA
No

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