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A13966 Methyl pyruvate, 98%

CAS Number
600-22-6
Synonyms
Pyruvic acid methyl ester
Methyl 2-oxopropionate

Stock No. Size Price ($) Quantity Availability
A13966-14 25g 30.80
A13966-22 100g 84.90
A13966-36 500g 321.00
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Methyl pyruvate, 98%

MDL
MFCD00008754
EINECS
209-987-4

Chemical Properties

Formula
C4H6O3
Formula Weight
102.09
Boiling Point
135-137°
Flash Point
39°(102°F)
Density
1.123
Refractive Index
1.4040
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in chloroform, methanol, ether, alcohol. Slightly soluble in water.

Applications

Methyl Pyruvate acts as a potent secretagogue used in the study of stimulus-secretion coupling. Also used in the preparation of quinoxalines as dual phoosphodiesterase 2/10 (PDE2/10) inhibitors. It increases free calcium ion concentration in the cytosol of pancreatic cells. It is used in the preparation of dimethyl 2,3-dimethylenebutanedioate.

Notes

Store away from oxidizing agent, heat.

Literature References

G. Bond, P.A. Meheux; A. Ibbotson; P.B. Wells. Origin of enhanced rate in the platinum-catalysed enantioselective hydrogenation of methyl pyruvate. Catalysis Today. 1991, 10 (3), 371-378.

I.M. Sutherland; A. Ibbotson; R.B. Moyes; P.B. Wells. Enantioselective hydrogenation I. Surface conditions during methyl pyruvate hydrogenation catalyzed by cinchonidine-modified platinum/silica (EUROPT-1). Journal of Catalysis. 1990, 125 (1), 77-88.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H317-H318-H335

Flammable liquid and vapour. May cause an allergic skin reaction. Causes serious eye damage. May cause respiratory irritation.

Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P261-P271-P272-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P333+P313-P363-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Avoid breathing dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,8021
Beilstein
1361953
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2918.30
TSCA
No

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