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D-Isosorbide is used as a reagent in the preparation of detergents, agrochemicals, cleansers, cosmetics and vasodilators. It is also employed as a pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives, which is used as vasodilators and coronary disease therapeutics. It is used in the treatment of hydrocephalus and glaucoma. It finds application as a building block for polymers like polycarbonates and polyesters.
Parikh, K.; Mistry, B.; Jana, S.; Gajaria, T.; Gupta, S.; Devkar, R. V.; Kumar, S. Isosorbide spacer containing gemini surfactants: surface and biochemical study. Colloid. Polym. Sci. 2015, 293 (5), 1437-1446.
Lavilla, C.; Munoz-Guerra, S. Sugar-based aromatic copolyesters: a comparative study regarding isosorbide and diacetalized alditols as sustainable comonomers. Green Chem. 2013, 15 (1), 144-151.