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652-67-5 - D-Isosorbide, 98% - 1,4:3,6-Dianhydro-D-glucitol - 1,4:3,6-Dianhydro-D-sorbitol - A13989 - Alfa Aesar

A13989 D-Isosorbide, 98%

CAS Number
652-67-5
Synonyms
1,4:3,6-Dianhydro-D-glucitol
1,4:3,6-Dianhydro-D-sorbitol

Size Price ($) Quantity Availability
50g 26.90
250g 76.10
1000g 276.00
*5x1kg 1363.00
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D-Isosorbide, 98%

MDL
MFCD00064827
EINECS
211-492-3

Chemical Properties

Formula
C6H10O4
Formula Weight
146.14
Melting point
56-64°
Sensitivity
Hygroscopic
Solubility
Soluble in alcohols, water and ketones.

Applications

D-Isosorbide is used as a reagent in the preparation of detergents, agrochemicals, cleansers, cosmetics and vasodilators. It is also employed as a pharmaceutical intermediate for dimethyl ether and mono- and dinitrate derivatives, which is used as vasodilators and coronary disease therapeutics. It is used in the treatment of hydrocephalus and glaucoma. It finds application as a building block for polymers like polycarbonates and polyesters.

Notes

Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Parikh, K.; Mistry, B.; Jana, S.; Gajaria, T.; Gupta, S.; Devkar, R. V.; Kumar, S. Isosorbide spacer containing gemini surfactants: surface and biochemical study. Colloid. Polym. Sci. 2015, 293 (5), 1437-1446.

Lavilla, C.; Munoz-Guerra, S. Sugar-based aromatic copolyesters: a comparative study regarding isosorbide and diacetalized alditols as sustainable comonomers. Green Chem. 2013, 15 (1), 144-151.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5224
Beilstein
80510
Harmonized Tariff Code
2932.99
TSCA
Yes
RTECS
LZ4380000

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