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Benzoic acid is an important precursor for the preparation of many other organic substances viz. benzoyl chloride, benylbenzoate, phenol, sodium benzoate, benzyl alcohol as well as benzoate plasticizers such as glycol-, diethhyleneglycol- and triethyleneglycol esters. Benzoic acid and its salts are used as food preservatives. It is involved in rubber polymerization as an activator and a retardant. It is the main component of benzoin resin and is a constituent of Whitfields ointment, which is used for the treatment of fungal skin diseases such as tinea, ringworm and athletes foot. It is widely used in cosmetics, dyes, plastics and insect repellents.
Sarcevica, I.; Orola, L.; Nartowski, K. P.; Khimyak, Y. Z.; Round, A. N.; Fabian, L. Mechanistic and Kinetic Insight into Spontaneous Cocrystallization of Isoniazid and Benzoic Acid. Mol. Pharmaceutics 2015, 12 (8), 2981-2992.
Osowole, A. A.; Wakil, S. M. Synthesis, characterization, antioxidant and antimicrobial activities of someMetal(II) Complexes of the Mixed-Ligands, Vitamin B2 and Benzoic acid. Appl. Chem. 2015, 79, 30370-30374.
Hazard Statements: H302-H318-H335
Harmful if swallowed. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P280f-P305+P351+P338
Wear protective clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.