I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
In the synthesis of organic compounds, phosphonium salts and other phosphorus compounds, and as a polymerization initiatorTriphenylphosphine is used in the synthesis of organic compounds due to its nucleophilicity and its reducing character. It is involved in the synthesis of biaryl compounds, phosphonium salts and other phosphorus compounds. As a reducing agent, it is used to prepare aromatic amines from the corresponding aromatic N-oxides. The anionic phosphine is usually isolated as the trisodium salt, which reacts with rhodium to form a complex that finds use in industrial hydroformylation reactions. It is also used to prepare Wilkinson's catalyst, RhCl(PPh3)3 useful to catalyze the hydrogenation of alkenes and tetrakis(triphenylphosphine)palladium(0) that is widely used to catalyse C-C coupling reactions in organic synthesis.
Lenstra, D. C.; Rutjes, F. P.; Mecinovic, J. Triphenylphosphine-catalysed amide bond formation between carboxylic acids and amines. Chem. Commun. 2014, 50 (43), 5763-5766.
Maleki, A.; Rahimi, R.; Maleki, S.; Hamidi, N. Synthesis and characterization of magnetic bromochromate hybrid nanomaterials with triphenylphosphine surface-modified iron oxide nanoparticles and their catalytic application in multicomponent reactions. RSC Adv. 2014, 4 (56), 29765-29771.
Hazard Statements: H302-H317-H373
Harmful if swallowed. May cause an allergic skin reaction. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P264b-P270-P272-P280g-P301+P312-P302+P352-P314-P330-P333+P313-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant