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Piperonylic acid is used as pharmaceutical intermediate.
Michel Schalk; Francisco Cabello-Hurtado; Marie-Agnes Pierrel; Rossitza Atanassova; Patrick Saindrenan; Daniele Werck-Reichhart. Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway. Plant Physiology. 1998, 118,(1), 209-218.
Esaac G.Esaac; John E.Casida. Piperonylic acid conjugates with alanine, glutamate, glutamine, glycine, and serine in living houseflies. Journal of Insect Physiology. 1968, 14,(7), 920-925.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.