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695-34-1 - 2-Amino-4-methylpyridine, 98% - 2-Amino-4-picoline - 4-Methyl-2-pyridinamine - A14177 - Alfa Aesar

A14177 2-Amino-4-methylpyridine, 98%

CAS Number
695-34-1
Synonyms
2-Amino-4-picoline
4-Methyl-2-pyridinamine

Size Price ($) Quantity Availability
25g 16.56
100g 27.19
500g 94.40
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2-Amino-4-methylpyridine, 98%

MDL
MFCD00006321
EINECS
211-780-9

Chemical Properties

Formula
C6H8N2
Formula Weight
108.14
Melting point
97-101°
Boiling Point
231°
Flash Point
118°(244°F)
Sensitivity
Hygroscopic
Solubility
Soluble in water (41 mg/ml at 20°C), lower alcohols (slightly), chloroform, ethyl acetate, and DMF.

Applications

2-Amino-4-methylpyridine has been used in the synthesis of 2-amino-4-methyl­pyridinium 2-hy­droxy­benzoate. It is potent inhibitor of NOS2 (iNOS) in vitro. It is used as pharmaceutical intermediate.

Notes

Hygroscopic. Incompatible with oxidizing agents and moisture. Store under dry inert gas. Protect from humidity and water. Store at -20°C.

Literature References

Madhukar Hemamalini; Hoong-Kun Fun. 2-Amino-4-methyl-pyridinium 2-hy-droxy-benzoate. Acta Crystallographica Section E.2010, 66 (Pt 8), o2151-o2152.

W S Faraci; A A Nagel; K A Verdries; L A Vincent; H Xu; L E Nichols; J M Labasi; E D Salter; E R Pettipher. 2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo. British Journal of Pharmacology.1996, 119 (6), 1101-1108.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H311-H315-H335-H318

Toxic if swallowed. Toxic in contact with skin. Causes skin irritation. May cause respiratory irritation. Causes serious eye damage.

Precautionary Statements: P280-P305+P351+P338-P309-P310-P337+P313

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. If eye irritation persists: Get medical advice/attention.

Other References

Merck
14,466
Beilstein
107066
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
TJ5150000

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