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A14197 3-Iodo-4-methylbenzoic acid, 98%

CAS Number
82998-57-0
Synonyms
3-Iodo-p-toluic acid

Stock No. Size Price ($) Quantity Availability
A14197-06 5g 33.80
A14197-14 25g 117.00
A14197-22 100g 341.00
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3-Iodo-4-methylbenzoic acid, 98%

MDL
MFCD00010392

Chemical Properties

Formula
C8H7IO2
Formula Weight
262.05
Melting point
206-210°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in methanol.

Applications

3-Iodo-4-methylbenzoic acid has been used in the preparation of unlabeled N-succinimidyl 4-guanidinomethyl-3-iodobenzoate (SGIMB) and boc-protected derivative of SGIMB (Boc-SGMIB).

Notes

Recommended storage temp 2-8°C. Store in cool, well ventilated area. Keep container tightly closed. Light Sensitive.

Literature References

G Vaidyanathan; D J Affleck; J Li, P Welsh; M R Zalutsky. A polar substituent-containing acylation agent for the radioiodination of internalizing monoclonal antibodies: N-succinimidyl 4-guanidinomethyl-3-[131I]iodobenzoate ([131I]SGMIB). Bioconjugate Chemistry. 2001, 12 (3), 428-438.

Ganesan Vaidyanathan; and Michael R Zalutsky. Synthesis of N-succinimidyl 4-guanidinomethyl-3-[*I]iodobenzoate: a radio-iodination agent for labeling internalizing proteins and peptides. Nature Protocols. 2007, 2 (2), 282-286.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2436216
Harmonized Tariff Code
2916.39
TSCA
No

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