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L-Glutamine is involved in many metabolic processes and regulates acid-base balance in the kidney. It is an important amino acid for the incorporation of ammonium ions into biomolecules. It is a vital component of culture media that serves as a major energy source for cells in culture. As a component in oral supplementation, it is useful for patients who have advanced stages of cancer to reverse cachexia (i.e. muscle wasting). It is also used for attention deficit-hyperactivity disorder (ADHD), a urinary condition called cystinuria, sickle cell anemia and for alcohol withdrawal support. It finds applications in patients with HIV (AIDS) to prevent weight loss.
He, Y. C.; Zhang, D. P.; Tao, Z. C.; Lu, Y.; Ding, Y.; Liu, F.; Zhu, Z. Z.; Rui, H.; Zheng, G. W.; Zhang, X. Improved biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by adding l-glutamine plus glycine instead of NAD+ in beta-cyclodextrin-water system. Bioresour. Technol. 2015, 182, 98-102.
Bonet, D. S.; Chisholm, D. J.; Holst, J. J.; Greenfield, J. R. L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients. Nutrients 2015, 7 (4), 2101-2108.
Hazard Statements: H315-H319-H320-H335-H336
Causes skin irritation. Causes serious eye irritation. Causes eye irritation. May cause respiratory irritation. May cause drowsiness or dizziness.
Precautionary Statements: P261-P264b-P271-P280g-P280i-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves. Wear eye/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant