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3-Fluoroaniline is used in the preparation of acetic acid-(3-fluoro-anilide by reacting with acetic acid anhydride. Further, it serves as a reagent in the preparation of radamide analogs as Grp94 inhibitors, which has potential to be antitumor agents.
Zhou, Y.; Yuan, Y.; You, L.; Anslyn, E. V. Dynamic Aminal-Based TPA Ligands. Chem. Eur. J. 2015, 21 (22), 8207-8213.
Yashkina, E. A.; Yashkin, S. N.; Svetlov, D. A.; Gorshkov, V. V. Themodynamics of adsorption and patterns of the gas-chromatographic retention of cyclic amines on surfaces of graphitized thermal carbon black. Russ. J. Phys. Chem. A 2015, 89 (9), 1672-1682.
Hazard Statements: H227-H302-H312-H331-H315-H319-H373
Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P201-P280a-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.