I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
1-Phenyl-1-propyne is used as a intermediate for phrama industry and chemical research.
Ki-Yeo Kim; Byoung-Kook Song; Sukmin Jeong; and Heon Kang. Adsorption Structures of Phenylacetylene and 1-Phenyl-1-propyne on a Si(100)-(2 × 1) Surface. J. Phys. Chem. B. 2003, 107 (43), 11987-11995.
H. Dietl; Horst Reinheimer; J. Moffat; Peter M. Maitlis. Reactions of acetylenes with noble-metal halides. VIII. Palladium cgloride catalyzed trimerization of 2-butyne and 1-phenyl-1-propyne. J. Am. Chem. Soc. 1970, 92 (8), 2276-2285.
2-Alkynes are metallated almost exclusively at the terminal position by t-BuLi in ether, in the presence of TMEDA. Subsequent reaction. e.g. with TMS chloride gives propargylic silanes: Synthesis, 111 (1984). Attempted lithiation with n-BuLi in THF, followed by alkylation, was found to give poor results. However, lithiation at -78o in the presence of HgCl2, allowed the monobenzylated product, 1,4-diphenyl-1-butyne, to be obtained in good yield: J. Org. Chem., 63, 3497 (1998).
Hazard Statements: H227-H315-H319
Combustible liquid. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant