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1-Phenyl-1-propyne is used as a intermediate for phrama industry and chemical research.
Ki-Yeo Kim; Byoung-Kook Song; Sukmin Jeong; and Heon Kang. Adsorption Structures of Phenylacetylene and 1-Phenyl-1-propyne on a Si(100)-(2 × 1) Surface. J. Phys. Chem. B. 2003, 107 (43), 11987-11995.
H. Dietl; Horst Reinheimer; J. Moffat; Peter M. Maitlis. Reactions of acetylenes with noble-metal halides. VIII. Palladium cgloride catalyzed trimerization of 2-butyne and 1-phenyl-1-propyne. J. Am. Chem. Soc. 1970, 92 (8), 2276-2285.
2-Alkynes are metallated almost exclusively at the terminal position by t-BuLi in ether, in the presence of TMEDA. Subsequent reaction. e.g. with TMS chloride gives propargylic silanes: Synthesis, 111 (1984). Attempted lithiation with n-BuLi in THF, followed by alkylation, was found to give poor results. However, lithiation at -78o in the presence of HgCl2, allowed the monobenzylated product, 1,4-diphenyl-1-butyne, to be obtained in good yield: J. Org. Chem., 63, 3497 (1998).
Hazard Statements: H227-H315-H319-H335
Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210u-P261-P280a-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.