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It finds its application in the reaction of the dilithio-derivative with an aldehyde, followed by conversion to the episulfide by reaction with ethyl chloroformate, and desulfurization with triethyl phosphite, leads to the (E)-2-alkenoic acid with high stereoselectivity. It is used as depilatories, hair straightening agent, hair waving agent, and reducing agent in cosmetic industry.
Kazuhiko Tanaka, et.al. New Methods for Synthesis of α,β-Unsaturated Carboxylic Esters from Carbonyl Compounds Using Monoanions of Dithiocarbonates, and Dianions of Ethyl Mercaptoacetate and Ethyl 2-Mercaptopropionate.Bull. Chem. Soc. Jpn.,1979,52(12), 3619-3625.
Vyacheslav Ya Sosnovskikh, et al. Unexpected synthesis of dihydrothienocoumarin derivatives from 2-trifluoromethylchromones and ethyl mercaptoacetate.Tetrahedron Lett.,2001,42(30), 5117-5119.
Reaction of the dilithio-derivative with an aldehyde, followed by conversion to the episulfide by reaction with ethyl chloroformate, and desulfurization with triethyl phosphite, leads to the (E)-2-alkenoic acid with high stereoselectivity: Synthesis, 127 (1983):
Hazard Statements: H226-H301
Flammable liquid and vapour. Toxic if swallowed.
Precautionary Statements: P260-P201-P280f-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.