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2-Amino-5-chlorobenzoic acid is used in the preparation of disease-modifying antirheumatic drugs (DMARDs). Also used to produce 6-chloro-3H-quinazolin-4-one at temperature of 180°C.
Stephen P. Coburn.; J. Dennis Mahuren. A versatile cation-exchange procedure for measuring the seven major forms of vitamin B6 in biological samples 1. Analytical Biochemistry. 1983, 129 (2), 310-317.
R. I. Fryer.; P. Zhang.; R. Rios. The Synthesis of Substituted 2-Aminophenyl Heterocyclic Ketones. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1993, 23 (7), 985-992.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.