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Thiophene-2-carboxaldehyde is used in the preparation of beta-aryl-beta-amino acids and urea derivatives. It acts as an arylation reagent. Further, it is used in the synthesis of unsaturated ketones, which serve as antiviral and cytotoxic agents. In addition to this, it is used as an intermediate to manufacture pharmaceuticals and aromatic compounds.
Sánchez, C. O.; Schott, E.; Zárate, X.; MacLeod-Carey, D.; Sobarzo, P.; Gatica, N. Effect of triphenylamine as electron-donor evenly spaced in 2, 4, 6 and 8 thiophene units of the main chain: synthesis and properties. Polym. Bull. 2015, 72 (4), 897-913.
Sánchez, C. O.; Sobarzo, P.; Gatica, N. Electronic and structural properties of polymers based on phenylene vinylene and thiophene units. Control of the gap by gradual increases of thiophene moieties. New J. Chem. 2015, 39 (10), 7979-7987.
Hazard Statements: H227-H302-H315-H317-H319
Combustible liquid. Harmful if swallowed. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation.
Precautionary Statements: P210-P261-P264b-P270-P272-P280-P301+P312-P302+P352-P305+P351+P338-P330-P333+P313-P337+P313-P362-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant