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98-03-3 - Thiophene-2-carboxaldehyde, 98+% - A14344 - Alfa Aesar

A14344 Thiophene-2-carboxaldehyde, 98+%

CAS Number
98-03-3
Synonyms

Size Price ($) Quantity Availability
100g 40.17
500g 151.20
1000g 327.54
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Thiophene-2-carboxaldehyde, 98+%

MDL
MFCD00005429
EINECS
202-629-8

Chemical Properties

Formula
C5H4OS
Formula Weight
112.15
Boiling Point
196-198°
Flash Point
78°(172°F)
Density
1.220
Refractive Index
1.5900
Sensitivity
Air Sensitive
Solubility
Miscible with chloroform, alcohol, ether, dimethylsulfoxide, ethyl acetate and most organic solvents. Immiscible with water.

Applications

Thiophene-2-carboxaldehyde is used in the preparation of beta-aryl-beta-amino acids and urea derivatives. It acts as an arylation reagent. Further, it is used in the synthesis of unsaturated ketones, which serve as antiviral and cytotoxic agents. In addition to this, it is used as an intermediate to manufacture pharmaceuticals and aromatic compounds.

Notes

Store in a cool place. Incompatible with strong bases, strong oxidizing agents and strong reducing agents.

Literature References

Sánchez, C. O.; Schott, E.; Zárate, X.; MacLeod-Carey, D.; Sobarzo, P.; Gatica, N. Effect of triphenylamine as electron-donor evenly spaced in 2, 4, 6 and 8 thiophene units of the main chain: synthesis and properties. Polym. Bull. 2015, 72 (4), 897-913.

Sánchez, C. O.; Sobarzo, P.; Gatica, N. Electronic and structural properties of polymers based on phenylene vinylene and thiophene units. Control of the gap by gradual increases of thiophene moieties. New J. Chem. 2015, 39 (10), 7979-7987.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H319-H227

Toxic if swallowed. Causes serious eye irritation. Combustible liquid.

Precautionary Statements: P210-P280-P264-P301+P310-P305+P351+P338-P321-P337+P313-P405-P403+P235-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). If eye irritation persists: Get medical advice/attention. Store locked up. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
105819
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
XM8135000

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