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Thiophene-2-carboxaldehyde is used in the preparation of beta-aryl-beta-amino acids and urea derivatives. It acts as an arylation reagent. Further, it is used in the synthesis of unsaturated ketones, which serve as antiviral and cytotoxic agents. In addition to this, it is used as an intermediate to manufacture pharmaceuticals and aromatic compounds.
Sánchez, C. O.; Schott, E.; Zárate, X.; MacLeod-Carey, D.; Sobarzo, P.; Gatica, N. Effect of triphenylamine as electron-donor evenly spaced in 2, 4, 6 and 8 thiophene units of the main chain: synthesis and properties. Polym. Bull. 2015, 72 (4), 897-913.
Sánchez, C. O.; Sobarzo, P.; Gatica, N. Electronic and structural properties of polymers based on phenylene vinylene and thiophene units. Control of the gap by gradual increases of thiophene moieties. New J. Chem. 2015, 39 (10), 7979-7987.
Hazard Statements: H227-H302-H319
Combustible liquid. Harmful if swallowed. Causes serious eye irritation.
Precautionary Statements: P210u-P280a-P305+P351+P338-P301+P312a-P403+P235-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.