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A14377 2-Mercaptoethylamine hydrochloride, 98+%

CAS Number
156-57-0
Synonyms
Aminoethanethiol hydrochloride
Cysteamine hydrochloride

Stock No. Size Price ($) Quantity Availability
A14377-14 25g 43.20
A14377-22 100g 129.00
A14377-36 500g 494.00
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2-Mercaptoethylamine hydrochloride, 98+%

MDL
MFCD00012904
EINECS
205-858-1

Chemical Properties

Formula
HSCH2CH2NH2•HCl
Formula Weight
113.61
Melting point
65-69°
Storage & Sensitivity
Keep Cold. Store under Nitrogen. Hygroscopic.
Solubility
Soluble in water, ethanol, methanol and dimethyl sulfoxide.

Applications

An inhibitor of DMBA-induced mammary tumors2-Mercaptoethylamine hydrochloride acts as a precursor in taurine biosynthesis and component of coenzyme A. It is involved in the preparation of active pharmaceutical ingredients like ranitidine and nizatidine. It acts as an antidote for acetaminophen poisoning. Further, it is used in the oral treatment of nephropathic cystinosis, radiation sickness and disorders of cysteine excretion. In addition to this, it serves as an antioxidant and an inhibitor of 7,12-Dimethylbenz[a]anthracene (DMBA)-induced tumors.

Notes

Store in a cool place. Hygroscopic. Incompatible with strong oxidizing agents.

Literature References

For selective protection of nitrogen by silylation, see: Synthesis, 924 (1980).

Bhattacharjee, S.; Lee, Y. R.; Ahn, W. S. Post-synthesis functionalization of a zeolitic imidazolate structure ZIF-90: a study on removal of Hg(II) from water and epoxidation of alkenes. CrystEngComm 2015, 17 (12), 2575-2582.

Yuan, Y. Y.; Du, J. Z.; Wang, J. Two consecutive click reactions as a general route to functional cyclic polyesters. Chem. Commun. 2012, 48 (4), 570-572.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,2779
Beilstein
3590083
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
KJ0200000

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