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461-89-2 - 6-Azauracil, 98% - 1,2,4-Triazine-3,5(2H,4H)-dione - A14389 - Alfa Aesar

A14389 6-Azauracil, 98%

CAS Number
461-89-2
Synonyms
1,2,4-Triazine-3,5(2H,4H)-dione

Size Price ($) Quantity Availability
5g 47.70
25g 189.00
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6-Azauracil, 98%

MDL
MFCD00006456
EINECS
207-318-0

Chemical Properties

Formula
C3H3N3O2
Formula Weight
113.08
Melting point
274-282°
Solubility
Partly soluble in water, ethanol, DMSO, and 1 M NH4OH (50 mg/ml).

Applications

6-Azauracil (6-AU) is used as a growth inhibitor of various microorganisms via depletion of intracellular GTP and UTP nucleotide pools. 6-Azauracil has been widely used in investigations on modulation of transcription, especially in yeast models.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Françoise Exinger and François Lacroute. 6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae.Current Genetics.,1992,22(1), 9-11.

J. Škoda.; V. F. Hess and F. Šorm. Production of 6-azauracil riboside by Escherichia coli growing in the presence of 6-azauracil.Collect. Czech. Chem. Commun.,1957,22(4), 1330-1333.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
116472
Harmonized Tariff Code
2933.69
TSCA
Yes
RTECS
XY7700000

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