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1466-76-8 - 2,6-Dimethoxybenzoic acid, 99% - A14418 - Alfa Aesar

A14418 2,6-Dimethoxybenzoic acid, 99%

CAS Number
1466-76-8
Synonyms

Size Price ($) Quantity Availability
25g 27.19
100g 73.23
500g 245.60
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2,6-Dimethoxybenzoic acid, 99%

MDL
MFCD00002437
EINECS
215-985-4

Chemical Properties

Formula
C9H10O4
Formula Weight
182.18
Melting point
ca 188° dec.
Solubility
Insoluble in water. Solubility in methanol is almost transparent. Soluble in DMSO, Ethyl Acetate and acetone.

Applications

It is used in the synthesis of indoles as well as coumarins related to Novobiocin, used as potent inhibitors of heat-shock protein 90 in the treatment of breast cancer.

Notes

Store away from bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Irrera S, et al. Supramolecular association in proton-transfer adducts containing benzamidinium cations. II. Concomitant polymorphs of the molecular salt of 2,6-dimethoxybenzoic acid with benzamidine.Acta Crystallogr C.,2012,68(11), 447-51.

Bian Q, et al. Fingerprint analysis and simultaneous determination of phenolic compounds in extracts of Curculiginis Rhizoma by HPLC-diode array detector.Chem Pharm Bull (Tokyo).,2013,61(8), 802-8.

GHS Hazard and Precautionary Statements

Hazard Statements: H319

Causes serious eye irritation.

Precautionary Statements: P305+P351+P338

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Beilstein
2212190
Harmonized Tariff Code
2918.99
TSCA
Yes
RTECS
DG8598725

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