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(4-Chlorophenylsulfonyl)acetonitrile react with trimethoxymethyl-benzene, and gives 2-(4-chloro-benzenesulfonyl)-3-methoxy-3-phenyl-acrylonitrile.
Chad E. Stephens; Matthew B. Price and J. Walter Sowell Sr. Synthesis of methyl 3-amino-4-aryl(or methyl)sulfonyl-2-thiophenecarboxylates from 3-alkoxy-2-aryl(or methyl)-sulfonylacrylonitriles. Journal of Heterocyclic Chemistry. 1999, 36 (3), 659-665.
Ghaneya Sayed Hassan; Hanan Hassan Kadry; Sahar Mahmoud Abou-Seri; Mamdouh Moawad Ali; Abeer Essam El-Din Mahmoud. Synthesis and in vitro cytotoxic activity of novel pyrazolo[3,4-d]pyrimidines and related pyrazole hydrazones toward breast adenocarcinoma MCF-7 cell line. Bioorganic & Medicinal Chemistry. 2011, 19 (22), 6808-6817.
Hazard Statements: H302-H312-H332-H500
Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. May form combustible dust concentrations in air
Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P312-P330-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Rinse mouth. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant