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5394-18-3 - N-(4-Bromobutyl)phthalimide, 98% - A14517 - Alfa Aesar

A14517 N-(4-Bromobutyl)phthalimide, 98%

CAS Number
5394-18-3
Synonyms

Size Price ($) Quantity Availability
5g 42.54
25g 166.59
100g 497.60
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N-(4-Bromobutyl)phthalimide, 98%

MDL
MFCD00005905
EINECS
226-401-2

Chemical Properties

Formula
C12H12BrNO2
Formula Weight
282.14
Melting point
77-81°
Boiling Point
165-170°/1mm
Solubility
Soluble in ethanol. Insoluble in water.

Applications

N-(4-Bromobutyl)phthalimide is used in organic synthesis and the production of pharmaceutical. It can react with 1-phenyl-piperazine to get N-[4-(4-phenyl-piperazin-1-yl)-butyl]-phthalimide. It is a useful synthesis reagent used to synthesize B-cyclodextrin derivatives.

Notes

Store at room temperature. Store away from oxidizing agents.

Literature References

S. Tomasi; M. Le Roch; J. Renault; J. C. Corbel and P. Uriac. N-alkylation of N1-mesitylenesulphonylputrescine with N-(4-bromobutyl)phthalimide: A Parallel Approach Using Multipin Solid-phase Synthesis. Pharmacy and Pharmacology Communications. 2000, 6 (4), 155-159.

Richard A. Glennon; Noreen A. Naiman; M. Edward Pierson; J. Doyle Smith; Abd M. Ismaiel; Milt Titeler; Robert A. Lyon. N-(phthalimidoalkyl) derivatives of serotonergic agents: a common interaction at 5-HT1A serotonin binding sites?. J. Med. Chem. 1989, 32 (8), 1921-1926.

Other References

Beilstein
164119
Harmonized Tariff Code
2925.19
TSCA
No

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