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2252-63-3 - 1-(4-Fluorophenyl)piperazine, 98% - 4-(1-Piperazinyl)fluorobenzene - A14541 - Alfa Aesar

A14541 1-(4-Fluorophenyl)piperazine, 98%

CAS Number
2252-63-3
Synonyms
4-(1-Piperazinyl)fluorobenzene

Size Price ($) Quantity Availability
5g 19.98
10g 34.30
25g 59.65
50g 100.31
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1-(4-Fluorophenyl)piperazine, 98%

MDL
MFCD00005960
EINECS
218-846-6

Chemical Properties

Formula
C10H13FN2
Formula Weight
180.23
Melting point
30-33°
Boiling Point
120°/0.1mm
Flash Point
>110°(230°F)
Refractive Index
1.5600
Sensitivity
Air Sensitive
Solubility
Insoluble in water.

Applications

1-(4-Fluorophenyl)piperazine was used in the synthesis of N,N-disubstituted piperazine. It is a major metabolite of niaparazine, a sedative, a hypnotic drug.

Notes

Air sensitive. Store under inert gas. Store away from air, oxidizing agents.

Literature References

Michael Collins; Marie-Claire Lasne and Louisa Barré. Rapid synthesis of N, N'-disubstituted piperazines. Application to the preparation of No carrier added 1-(4-[18F] fluorophenyl) piperazine and of an [18F]-selective ligand of serotoninergic receptors (5HT2 antagonist). J. Chem. Soc., Perkin Trans. 1, 1992, (23), 3185-3188.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H314

Toxic if swallowed. Causes severe skin burns and eye damage.

Precautionary Statements: P260-P280-P301+P310-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
610723
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2933.59
TSCA
No

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