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A14543 2-Oxazolidinone, 99%

CAS Number
497-25-6
Synonyms
2-Oxazolidone

Stock No. Size Price ($) Quantity Availability
A14543-14 25g 40.00
A14543-22 100g 110.00
A14543-36 500g 372.00
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2-Oxazolidinone, 99%

MDL
MFCD00005268
EINECS
207-840-9

Chemical Properties

Formula
C3H5NO2
Formula Weight
87.08
Melting point
84-89°
Boiling Point
220°/48mm
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

2-Oxazolidinone is used as antimicrobials, in organisms it act as a protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. They are used for chiral synthesis. It has been used as an ethanolamine equivalent, also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives.

Notes

Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.

Literature References

Hideaki Kakeya; Masayuki Morishita; Hiroyuki Koshino; Tetsu-ichiro Morita; Kimiko Kobayashi and Hiroyuki Osada. Cytoxazone:? A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp. J. Org. Chem. 1999, 64 (3), 1052-1053.

Guo-Jie Ho; David J. Mathre. Lithium-Initiated Imide Formation. A Simple Method for N-Acylation of 2-Oxazolidinones and Bornane-2,10-Sultam. J. Org. Chem. 1995, 60 (7), 2271-2273.

Has been used as an ethanolamine equivalent, e.g. in reaction with succinic anhydride to give 1-(2-hydroxyethyl)succinimide: Tetrahedron, 44, 261 (1988). Also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives: J. Org. Chem., 57, 6257 (1992).

Other References

Beilstein
106251
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
RQ2450000

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