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607-67-0 - 4-Hydroxy-2-methylquinoline, 98+% - 4-Hydroxyquinaldine - 2-Methyl-4-quinolinol - A14587 - Alfa Aesar

A14587 4-Hydroxy-2-methylquinoline, 98+%

CAS Number
607-67-0
Synonyms
4-Hydroxyquinaldine
2-Methyl-4-quinolinol

Size Price ($) Quantity Availability
5g 39.98
25g 134.93
100g 393.60
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4-Hydroxy-2-methylquinoline, 98+%

MDL
MFCD00006758
EINECS
210-140-6

Chemical Properties

Formula
C10H9NO
Formula Weight
159.19
Melting point
234-236°
Solubility
Slightly soluble in water.

Applications

4-Hydroxy-2-methylquinoline is act as an intermediate in the synthesis of dequalinium chloride and as pharmaceutical intermediate.

Notes

Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.

Literature References

Thomas J. Lanza; Philippe L. Durette; Thomas Rollins; Salvatore Siciliano; Dana N. Cianciarulo; Sumire V. Kobayashi; Charles G. Caldwell; Martin S. Springer; William K. Hagmann.Substituted 4,6-diaminoquinolines as inhibitors of C5a receptor binding. J. Med. Chem. 1992, 35 (2), 252-258.

Elise A.Brandenburger Brown; John E Franklin; Eileen Pratt; Eberhard G Trams. Contributions to the pharmacology of quinaldine (uptake and distribution in the shark and comparative studies). Comparative Biochemistry and Physiology Part A: Physiology. 1972, 42 (1), 223-231.

4-Hydroxy-2-methylquinolines may be converted to benzo[a]acridines by condensation with aryl aldehydes followed by a photochemical cyclization: Synthesis, 217 (1991).

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
118320
Harmonized Tariff Code
2933.49
TSCA
No

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