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4-Hydroxy-2-methylquinoline is act as an intermediate in the synthesis of dequalinium chloride and as pharmaceutical intermediate.
Thomas J. Lanza; Philippe L. Durette; Thomas Rollins; Salvatore Siciliano; Dana N. Cianciarulo; Sumire V. Kobayashi; Charles G. Caldwell; Martin S. Springer; William K. Hagmann.Substituted 4,6-diaminoquinolines as inhibitors of C5a receptor binding. J. Med. Chem. 1992, 35 (2), 252-258.
Elise A.Brandenburger Brown; John E Franklin; Eileen Pratt; Eberhard G Trams. Contributions to the pharmacology of quinaldine (uptake and distribution in the shark and comparative studies). Comparative Biochemistry and Physiology Part A: Physiology. 1972, 42 (1), 223-231.
4-Hydroxy-2-methylquinolines may be converted to benzo[a]acridines by condensation with aryl aldehydes followed by a photochemical cyclization: Synthesis, 217 (1991).
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.