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The acid chloride readily forms the oxazoline, which can be coupled with Mg or Li reagents (alkyl or aryl), with displacement of the o-methoxy group, to give alkylated or arylated products: Org. Synth. Coll., 9, 258 (1998); for an example, see 2-Amino-2-methyl-1-propanol, A17814./n
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P280g-P305+P351+P338
Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.