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A14695 Tricine, 98+%

CAS Number
5704-04-1
Synonyms
N-(Trishydroxymethylmethyl)glycine

Stock No. Size Price ($) Quantity Availability
A14695-14 25g 22.80
A14695-22 100g 56.40
A14695-36 500g 211.00
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Tricine, 98+%

MDL
MFCD00004277
EINECS
227-193-6

Chemical Properties

Formula
(HOCH2)3CNHCH2CO2H
Formula Weight
179.17
Melting point
ca 183° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

Good's buffers Tricine is used as an electrophoresis buffer and involved in the separation of low molecular weight proteins and peptides. It operates in the pH range between 7.4 and 8.8. It acts as an effective scavenger of hydroxyl radicals during the study of radiation-induced membrane damage. It is also used in resuspension of cell pellets.

Notes

pH range: 7.8-8.8Incompatible with strong oxidizing agents.

Literature References

Biological buffer, pKa = 8.15 at 20o: Biochemistry, 5, 467 (1966).

Ying, Y.; Zhao, L.; Kong, L.; Kong, X.; Hua, Y.; Chen, Y. Solubilization of proteins in extracted oil bodies by SDS: A simple and efficient protein sample preparation method for Tricine-SDS-PAGE. Food Chem. 2015, 181, 179-185.

Tapeinou, A.; Androutsou, M. E.; Kyrtata, K.; Vlamis-Gardikas, A.; Apostolopoulos, V.; Matsoukas, J.; Tselios, T. Conjugation of a peptide to mannan and its confirmation by tricine sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal. Biochem. 2015, 485, 43-45.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,9651
Beilstein
1937804
Harmonized Tariff Code
2922.50
TSCA
Yes

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