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6-Aminohexanoic acid is used as an intermediate in the polymerization of Nylon-6. It is involved in the extraction of aldehydes from the reaction mixture as well as to improve the solubilization of membrane proteins in electrophoresis. It acts as an inhibitor of fibrinolysis.
Has been recommended as a reagent for the extraction of aldehydes from reaction mixtures, giving better recovery than bisulfite: Chem. Pharm. Bull., 28, 1917 (1980)./n
Gamez, L. M.; Franco, L.; Casas, M. T.; Puiggali, J. Crystallization studies on a clay nanocomposite prepared from a degradable poly(ester amide) constituted by glycolic acid and 6-aminohexanoic acid. Polym. Eng. Sci. 2011, 51 (8), 1650-1661.
Sattler, J. H.; Fuchs, M.; Mutti, F. G.; Grischek, B.; Engel, P.; Pfeffer, J.; Woodley, J. M.; Kroutil, W. Introducing an In?Situ Capping Strategy in Systems Biocatalysis To Access 6-Aminohexanoic acid. Angew. Chem. 2014, 126 (51), 14377-14381.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant