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148-24-3 - 8-Hydroxyquinoline, 99% - 8-Quinolinol - Oxine - A14720 - Alfa Aesar

A14720 8-Hydroxyquinoline, 99%

CAS Number
148-24-3
Synonyms
8-Quinolinol
Oxine

Size Price ($) Quantity Availability
100g 30.69
500g 93.60
2500g 420.24
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8-Hydroxyquinoline, 99%

MDL
MFCD00006807
EINECS
205-711-1

Chemical Properties

Formula
C9H7NO
Formula Weight
145.16
Melting point
72-76°
Boiling Point
267°
Sensitivity
Light Sensitive
Solubility
Almost insoluble in water and diethyl ether. Highly soluble in ethanol, acetone, chloroform, and benzene.Soluble in acetic acid, ethanol, acetone, chloroform, benzene and aqueous mineral acids. Insoluble in water and diethylether.

Applications

8-Hydroxyquinoline is used as an antiseptic and disinfectant. Its alcoholic solution is used in liquid bandages. It is used to prepare tris(8-hydroxyquinolinato)aluminum, which finds application as a component of organic light-emitting diodes (OLED's). It is also used as a reagent and as a stabilizer of hydrogen peroxide in a rocket fuel oxidizer. It is used as a chelating agent and used as a carrier for radio-indium for diagnostic purposes. Its halogenated derivatives are used as anti-infective agents and oral antiamebics.

Notes

Light sensitive. Incompatible with oxidizing agents.

Literature References

Chelating ligand.

Thinnes, C. C.; Tumber, A.; Yapp, C.; Scozzafava, G.; Yeh, T.; Chan, M. C.; Tran, T. A.; Hsu. K.; Tarhonskaya, H.; Walport, L. J.; Wilkins, S. E.; Martinez, E. D.; Müller, S.; Pugh, C. W.; Ratcliffe, P. J.; Brennan, P. E.; Kawamura, A.; Schofield, C. J. Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases. Chem. Commun. 2015, 51 (84), 15458-15461.

Liang, S. H.; Southon, A. G.; Fraser, B. H.; Krause-Heuer, A. M.; Zhang, B.; Shoup, T. M.; Lewis, R.; Volitakis, I.; Han, Y.; Greguric, I.; Bush, A. I.; Vasdev, N. Novel fluorinated 8-hydroxyquinoline based metal ionophores for exploring the metal hypothesis of Alzheimer’s disease. ACS Med. Chem. Lett. 2015, 6 (9), 1025-1029.

GHS Hazard and Precautionary Statements

Hazard Statements: H341-H302

Suspected of causing genetic defects. Harmful if swallowed.

Precautionary Statements: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,4843
Beilstein
114512
Harmonized Tariff Code
2933.49
TSCA
Yes
RTECS
VC4200000

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