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4-Nitrobenzoic acid used as an intermediate for bulk drugs especially in the manufacturing of folic acid and in the manufacturing of PABA, DABA & dye intermediate.
Hyouk Soo Han; Sang Woo Han; Chang Hwan Kim; Kwan Kim. Adsorption and reaction of 4-Nitrobenzoic acid on ω-functionalized alkanethiol monolayers on powdered silver:? Infrared and raman spectroscopy study. Langmuir. 2000, 16, (3),1149-1157
Hyouk Soo; Han Chang; Hwan Kim; Kwan Kim. Diffuse Reflectance Infrared Spectra of 4-Nitrobenzoic Acid and 4-Cyanobenzoic Acid Self-Assembled on Fine Silver Particles. Applied Spectroscopy. 1998, 52, (8),1047-1052
Selective reduction of the carboxyl group to the alcohol can be achieved in 94% yield using Benzyltriethylammonium borohydride, B24952, in combination with TMS chloride. Esters are unaffected under these conditions: Synth. Commun., 20, 907 (1990). See also, J. Chem. Soc., Chem. Commun., 903 (1989).
Hazard Statements: H302-H319
Harmful if swallowed. Causes serious eye irritation.
Precautionary Statements: P264b-P270-P280i-P301+P312-P305+P351+P338-P330-P337+P313-P501c
Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear eye/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If eye irritation persists: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant